Sex-biased expression of the TLR7 gene in severe COVID-19 patients: Insights from transcriptomics and epigenomicsArticle Published on 2022-12-012022-11-16 Journal: Environmental research [Category] 유전자 메커니즘, [키워드] acute phase analyzed Blood Cohort coronavirus disease COVID-19 COVID-19 patient CpG DNA DNA methylation dose downregulated embryogenesis epidemiological data epigenomic epigenomics Evidence expression female females gene product Genetic variation Genome-wide association studies Host inactivation incidence incidence of COVID-19 independent insight long-COVID-19 male males Methylation n-Counter. nasal patients Post-infection RNAseq Saliva Severe case severe COVID-19 severity Sex significantly higher stratified suggested timepoint TLR7 TLR7 gene transcriptomics with COVID-19 [DOI] 10.1016/j.envres.2022.114288 PMC 바로가기
Genomic and epidemiologic surveillance of SARS-CoV-2 in Southern Brazil and identification of a new Omicron-L452R sublineageArticle Published on 2022-11-012022-11-16 Journal: Virus research [Category] SARS, 변종, 유전자 메커니즘, [키워드] Amino acid B.1.1.529 Brazil Characteristics COVID-19 cases delta variant dominant Epidemiologic surveillance epidemiological data Genetic increase in information knowledge mutated Mutation mutational scanning omicron pandemic replaced Research resulting S:L452R SARS-CoV-2 the SARS-CoV-2 variant VoC VOC. [DOI] 10.1016/j.virusres.2022.198907 PMC 바로가기
A novel method to monitor COVID-19 fatality rate in real-time, a key metric to guide public health policyArticle Published on 2022-10-312022-11-16 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] applied approach changes in COVID-19 Delta driven by early phase Effect Epidemic Epidemics epidemiological data Fatality rate fused Germany high accuracy Infection MONITOR omicron pandemic public health required sensitivity vaccination Vaccine variant [DOI] 10.1038/s41598-022-23138-4 PMC 바로가기
The Possible Impact of Nationwide Vaccination on Outcomes of the COVID-19 Epidemic in North Korea: A Modelling StudyArticle Published on 2022-10-242022-11-16 Journal: Journal of Korean medical science [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome Analysis Asymptomatic B.1.1.529 calibrated compartmental model coronavirus coronavirus disease COVID-19 COVID-19 case COVID-19 transmission COVID-19 vaccination Democratic People's Republic of Korea dose Epidemic epidemiological epidemiological data Epidemiological models exacerbated Hospitalization Impact incidence indicated lack lifted measure National North Omicron variant outcome parameter Prevalence prevalence of COVID-19 projection proportion proportions public health reduced reported Risk assessment Spread suggested suppress suppressed the disease Transmissibility vaccination vaccination. Vaccine was used [DOI] 10.3346/jkms.2022.37.e300 PMC 바로가기
Cov2clusters: genomic clustering of SARS-CoV-2 sequencesArticle Published on 2022-10-192022-11-16 Journal: BMC Genomics [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Accuracy advance approach bioinformatics Canada Cluster Clustering Combination COVID-19 pandemic epidemiological data epidemiologically Evidence genomic Genomic analysis global public health high accuracy High-resolution identify identifying increase in management mimicking pandemic pathogen Phylogenetic Phylogenetic tree produced producing Public public health Repository SARS-CoV-2 SARS-CoV-2 sequence SARS-CoV-2 sequence data sequence sequencing technology stability Surveillance the disease Transmission viral pathogen WGS whole genome sequence Whole genome sequencing whole genome sequencing. [DOI] 10.1186/s12864-022-08936-4 PMC 바로가기
Surveillance of omicron variants through wastewater epidemiology: Latest developments in environmental monitoring of pandemic폐수 역학을 통한 오미크론 변이체 감시: 전염병의 환경 모니터링에 대한 최신 개발Review Published on 2022-10-152022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] assessment B.1.1.529 benefit Biomarker Biomarkers caused contagious disease contagious diseases COVID-19 Early detection early warning environmental health Epidemics epidemiological data Epidemiology Evidence examined Examining followed by Health health information help Human Human health risks IMPROVE infection control infectious Infectious disease information initial Intervention Omicron variant outbreak pandemic plant Prevent Prevention strategy problem progression provided reduce Research SARS-CoV-2 SARS-CoV-2 B.1.1.529 Spread Surveillance the disease Therapies Transmission Treatment variant variant of concern virus wastewater Wastewater epidemiology. water Work environment workstation [DOI] 10.1016/j.scitotenv.2022.156724 PMC 바로가기 [Article Type] Review
Inflammation Causes Exacerbation of COVID-19: How about Skin Inflammation?Article Published on 2022-10-142022-11-16 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] accumulated aging atopic atopic dermatitis bat bat coronaviruses cause Cell China conditions coronavirus COVID-19 Diabetes Mellitus disease Diseases enzyme epidemiological data Europe Exacerbation help highest homology Host Human humans hypertension infect Inflammation Inflammatory inflammatory condition mechanism membrane fusion Middle East occurred poor prognosis promote psoriasis pulmonary disease receptor ACE2 SARS-CoV-2 skin skin. TMPRSS viral infection virus [DOI] 10.3390/ijms232012260 PMC 바로가기
Impact of antigen test target failure and testing strategies on the transmission of SARS-CoV-2 variantsArticle Published on 2022-10-052022-11-15 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] absence amino-acid Antigen compartmental model country COVID-19 diagnostic epidemiological data genomic highlight identify Impact increasingly Italian Italy limitation molecular Molecular tests N antigen Population SARS-CoV-2 variant Sequencing Spread Substitution Surveillance the N protein transmission of SARS-CoV-2 variant variants Veneto widespread [DOI] 10.1038/s41467-022-33460-0 PMC 바로가기
Risk factors associated with hospitalization in patients with asymptomatic or mild COVID-19 in public accommodation facilities in TokyoObservational Study Published on 2022-10-012022-10-04 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 임상, [키워드] Admission age association Care conducted coronavirus disease COVID-19 COVID-19 patient Cox regression Cox regression analysis Cox regression model diabetes epidemiological data evaluated Factor Fever Gout groups hazard ratio high risk Hospitalization Hospitalized hospitalized patient Japan medical intervention medication Mild obesity Observational cohort study Oxygen administration Patient patients with asymptomatic patients with COVID-19 provided psychiatric disease Psychiatric medication Recovery accommodation facility. required risk factor sensitivity analysis severe respiratory symptoms significantly higher Symptom the median Tokyo underlying disease [DOI] 10.1016/j.jiac.2022.06.002 PMC 바로가기 [Article Type] Observational Study
Unexpected details regarding nosocomial transmission revealed by whole-genome sequencing of severe acute respiratory coronavirus virus 2 (SARS-CoV-2)Article Published on 2022-10-012022-11-16 Journal: Infection Control and Hospital Epidemiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] age analysis Analysis clade Clinical characteristics cohort study collected coronavirus disease COVID-19 Deceased died epidemiological epidemiological data evaluate event Genetic HCW HCWs healthcare worker hospital identify indicated Infection prevention knowledge male measure Measures mechanism median medical records nasopharyngeal sample nosocomial nosocomial COVID-19 Nosocomial infection NPs outbreak outcome Patient patients performed Phylogenetic analysis positive provided Respiratory Coronavirus RNA SARS-CoV-2 selected significantly higher subclade supported Transmission viral clade virus WGS whole-genome sequencing [DOI] 10.1017/ice.2021.374 PMC 바로가기